However, having them increases the likelihood of developing diabetes. And both diabetes and high triglycerides increase the risk of heart disease which can lead to heart attack or stroke, so having both compound that risk. While diabetes has several warning signs and symptoms, high triglycerides usually do not. Per the Mayo Clinic results are categorized as follows:.
A healthy lifestyle can help reduce high triglycerides and manage diabetes, including maintaining a healthy weight and diet, regular exercise, reducing alcohol intake, and quitting smoking.
Several medications are also available for lowering triglycerides, including fibric acid derivative medications and nicotinic acid, which also have an effect on cholesterol. If diagnosed, both diabetes and high triglycerides can be managed and complications can be minimized. In conclusion, we showed a graded positive association between elevated TG levels and inadequate glycemic control for patients with insulin-treated type 2 diabetes mellitus in China.
The results from this study imply that in these patients treated with a sufficient dose of insulin, elevated TG levels may be an independent and strong factor contributing to inadequate glycemic control. The authors thank all the health professionals who were involved in the CNHSS study for their contributions to data collection and quality control.
All authors contributed to drafting, modifying, and approving the manuscript and take responsibility for its accuracy and integrity. Disclosure Summary: The authors have nothing to disclose. Prevalence and ethnic pattern of diabetes and prediabetes in China in Google Scholar. N Engl J Med. Follow-up of glycemic control and cardiovascular outcomes in type 2 diabetes. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.
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The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux. J Clin Invest. Diabetes Obes Metab. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Sign In. Advanced Search. Search Menu. Article Navigation. The list below includes common causes for people who have type 2 diabetes and related problems:.
Poorly-controlled type 2 diabetes : When your diabetes is not well-managed, you are more likely to have high levels of both glucose blood sugar and insulin in your body. Insulin helps convert glucose into glycogen the stored form of glucose and helps to store glycogen in the liver.
When the liver becomes too saturated with glycogen, though, glucose is instead used to create fatty acids that are released into the bloodstream. These fatty acids are used to make triglycerides, which build up in fat cells and contribute to body fat. Eating more calories than you burn : Triglycerides are used as a quick energy source between meals. Leftover calories are stored in your body cells as triglycerides. High carbohydrate intake : When you eat foods with carbohydrates, the digestive system breaks the food down and extracts glucose.
The glucose is then absorbed through the intestines into the bloodstream. As described above with poorly controlled diabetes, excess glucose can be used to make triglycerides. Not all carbohydrates are unhealthy foods, however, if you overeat carbohydrates your triglycerides can increase. Obesity : Being obese or overweight is not a guarantee that you will develop high levels of triglycerides, but there is a correlation between obesity and hypertriglyceridemia.
There is a stronger correlation between excess waist circumference and high levels of triglycerides than with body mass index. Insulin resistance : Insulin resistance occurs when your body does not respond to the insulin you make—as a result, sugar cannot enter the cells and instead remains in the bloodstream.
Being resistant to the action of insulin contributes to high levels of both insulin and glucose and can lead to uncontrolled diabetes. Of course, uncontrolled diabetes can lead to high triglycerides, as described above. Renal failure : The risk of chronic renal kidney failure is increased in people with diabetes.
In fact, diabetes is one of the most common cause. Renal failure causes problems with the regulation of blood fats and results in high triglyceride levels. This could be due to increased triglyceride production, or the inability to clear them from the bloodstream, or both.
Renal failure can also cause or worsen insulin resistance. Genetics : Problems with high triglycerides can run in families. If this is the case, affected family members may have xanthelasma, or yellowish fatty deposits under the skin.
A study found that low HDL cholesterol and high triglyceride levels due to genetic predisposition is related to increased risk for type 2 diabetes. Low thyroid hormone levels : Thyroid disorders appear to have a higher prevalence in people with diabetes. The most common disorder is an underactive thyroid or hypothyroidism.
If you have both high triglyceride and cholesterol levels, it might be a sign of low thyroid hormone levels. Ask your healthcare provider about ruling out this disorder. Treatment for hypothyroidism may help lower triglyceride levels. Medications : Certain medications, such as birth control pills, estrogen, beta blockers, diuretics, steroids, retinoids, protease inhibitors, and Tamoxifen, can increase triglyceride levels.
If you are taking one or more of these medications, talk to your healthcare provider about treatment options. Do not stop taking these medications without your healthcare provider's guidance.
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